Ultra-high molecular weight polyethylene (UHMW PE) boron-containing panels are used as neutron shielding materials, suitable for BNCT treatment rooms, medical accelerator rooms, nuclear medicine waste storage, and wall or protective door linings. These panels are self-lubricating, anti-static, and non-ferromagnetic, so they won’t interfere with magnetic fields, with stable and reliable neutron shielding performance. The panels are lightweight, easy to install, non-toxic, and free of lead pollution, making them compatible with sealed hospital protective environments, and low in maintenance costs. Custom shapes and boron content are supported, making them a high-quality solution for safe, eco-friendly, and lightweight medical neutron radiation protection projects.